"We wish him well and we absolutely respect the work he has done and he has been doing amazing things. He spent five years working on it. But his is a business that's very specific to what he is doing, and it would probably be better for him to be based in Auckland, where there are far bigger networks within that field,." Ms Kiro said.
She had recently opened a business in Kaitaia — Kiro Management — which operated in the town and in Auckland. She felt there were plenty of business opportunities in Kaitaia and surrounds.
"From a business association point of view part of our annual plan will be looking at how we can attract more businesses to town."
She felt that Kaitaia was in Dr O'Sullivan's heart and he would be back one day.
Te Runanga o Te Rarawa chairman Haami Piripi said it had been a privilege to have somebody of Dr O'Sullivan's standing working for the people of the Far North and it was sad to see him leave.
"I think this is an inevitable development in terms of where Lance is going to as a leader in his own right. To be a leader in his field and continue to achieve the great feats his is, he needs to move where the population is greatest to do that," Mr Piripi said.
"But with technology Lance will only be a push of a button away."
He said Dr O'Sullivan had left a legacy of innovation and using the latest technology to get best practice and the best health and education outcomes for people.
"This is a big loss for us, but he will go on to make far greater contributions to our society."
Felicity Foy, Far North District Councillor for the Te Hiku ward, said it's sad for the town that Dr O'Sullivan has to leave to grow his business.
"I hope he keep his house up here and that he and his family return. We really should be thankful and proud that he is a member of our community," Ms Foy said.
"He has had a really positive effect on our community, with him being New Zealander of the year and also standing up for our people and showing our high levels of depravation and going to central government with that."
She said there were more than enough business opportunities in the district and it was up to the Far North District Council to help facilitate them.
Ms Foy said the elderly care sector, health and tourism were areas that could be looked at, while taking advantage of the district's natural beauty.
Regional Development Minister Shane Jones, from the Far North, said it was disappointing but did not mean Kaitaia could not sustain good businesses.
"I'm sure lots of people have relied on Dr Lance and I wish him well. But the disappearance of Dr Lance must not be catastrophised," Mr Jones said.
"There is no shortage of other businesspeople in Kaitaia. His is a distinctive case in terms of wanting to develop a new medical product and new medical services."
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