State Highway 1 is closed south of Whangārei between Rewa Rewa Rd and Tauroa St following a serious crash this afternoon.
Hato Hone St John was notified at 2.50pm and transported two patients to Whangārei Hospital.
One person was in a serious condition and another in a moderate condition.
New Zealand Transport Agency Waka Kotahi advised the road would remain closed for some time while the Serious Crash Unit investigates.
Motorists are advised to delay their journeys or allow for extra time to follow the detours.
