3.10pm UPDATE
The driver and sole occupant of a northbound vehicle involved in the crash has died at the scene.
A woman from a second, southbound vehicle has been taken to Whangarei Hospital with serious injuries.
Police say the highway will remain closed for up to three more hours.
Diversions are still in place.
1.35pm UPDATE
One person from each of the cars were trapped. Both have been freed and St John staff are treating the patients.