One person was taken to hospital in Hawke's Bay Rescue Helicopter and two by road ambulance after another crash on State Highway 5, this time near Te Pohue.
The single-vehicle crash comes the day after a fatal crash on the Napier-Taupo Rd. Two people died and three people were hospitalised near Rangataiki.
Hawke's Bay Rescue Helicopter Trust general manager Ian Wilmot said three people were in the vehicle.
"We transported a female patient in her mid-20s, who had been a passenger in the vehicle," he said. "She suffered head, shoulder and arm injuries from the accident."
Wilmot added: "The two others were transported by road ambulance."