Three vehicles are reported to have been involved in a crash which has caused injuries to seven people and closed State Highway 2 between Dannevirke and Woodville.
Police said the crash happened in the Papatawa area about 3.38pm on Friday, and that one person was reported to have serious injuries and six others had moderate injuries.
At least one helicopter was among the emergency services response, and motorists were being asked to avoid the area and the route during the emergency.
The road was understood to be still closed to traffic at 4.30pm.