A crash between a motorcycle and a car closed the State Highway 2 Oringi North overbridge, near Dannevirke.
Emergency services responded to a serious two-vehicle crash about 2pm. Police said initial indications suggested one person had serious injuries.
Motorists were advised to avoid the area and use alternative routes where possible.
The road was closed between Kiritaki Rd and Graham Rd. It reopened on Friday evening.
