Daughter Josie Russell said the work came from Warkworth to Banks Peninsula and everywhere in between.
"We even have two pieces from Brisbane this year, which is great."
Daughter and co-organiser Lizzie Russell said the event was a true celebration of spring, art, Hawke's Bay and what the Cranford Hospice does for the region.
"We are delighted. We have got artists, sponsors, local art buyers and lovers all here. It should be a week of fun," Ms Russell said.
Ms Russell, said they had already sold a wide variety of work in the first couple of hours and sales were going well.
"We still have a lot more on offer so I encourage people to come and explore the garden."
Cranford Hospice, CEO, Janice Byford-Jones, said the support was amazing.
"What a fantastic community we have, people like the Russell's opening up their home for us is incredible. Everyone here has come to support us, which then allows us to provide care at no cost, it means so much."
Member of the board, Frane Rosandich, said the support the hospice received allowed Cranford to stand and stand very tall.
"The Russell's had a vision and you can now see the fruits of their sowing."
The expedition, held at 125 Rosser Rd, runs until November, 13 and is open from 10am-6pm every day.
On Friday evening they are holding a special event, Wildflower at Twilight, which will feature band Mid-Life Crisis and a variety of food trucks.
"It will be a fun night for a cost of $25 per person," Ms Russell said.
The expedition to date has raised about $150,000 and this year should be another significant contribution.