But as the Titans mounted a last-ditch attack, Souths halfback Chris Sandow was penalised and sin-binned in the final minute for Prince to level the scores by coolly slotting home.
In a rugged match, Souths took full advantage of the 63rd-minute sin-binning of Nathan Friend to almost get out of jail, with centre Beau Champion bagging a double for the night.
But they now start their much-hyped season none from two after last week's shock 36-10 thumping at the hands of the Sydney Roosters.
The Titans have won both their opening games in come-from-behind performances, after last week's 24-18 victory over the Vodafone Warriors.
In Woollongong last night, St George Illawarra firmed as NRL premiership favourites after a Brett Morris hat-trick propelled them to victory over Canterbury last night.
The Dragons blew away the opposition with a stunning opening burst which yielded 16 unanswered points in as many minutes.
They wasted little time in getting fans on their feet, with a Morris swan dive making it 6-0 off the back of a brilliant Darius Boyd cut-out pass.
Their next points came after the Bulldogs' defence opened up on their own line for Dean Young to go through untouched, and it was all the home side when Morris had his second following a Matt Prior bust inside his own half.
Bulldogs veteran Brett Kimmorley did his best to extend the Dragons' lead as he gave up two penalties and dropped the ball all inside the first six minutes of the second half.
The Bulldogs finally earned themselves a repeat set 10 minutes into the second stanza, and the sustained period of attack paid dividends as Ben Barba danced his way over.
Their momentum was crushed when Gary Warburton gave away a dubious flop penalty near the Dragons' line, the home side weathering the Canterbury surge before Morris completed his hat-trick three minutes from time.
- AAP